Aim:

To determine and compare gender and age-based normative P100 latency and amplitude values in our laboratory.

Materials and Methods:

100 adults (75 female+25 male) were included in the study. VEP pattern was performed to both eyes, separately to each one. P100 latencies and amplitudes were compared between the two eyes in terms of gender and age.

Results:

The ages of the participants were between 10.18 and 64.47 and the mean age was 39.07 ± 12.57 years. The average of latency determined in females was 107.15 ± 4.56 in the right and 108.12 ± 4.6 in the left, in males was 110.2 ± 4.78 in the right and 111.76 ± 4.47 in the left. Bilateral P100 latencies were detected longer in males. The amplitude values were 9.09 ± 5.05 in females and 7.32 ± 2.48 in males. There was a statistically negative significant correlation between amplitude measurements in the right eyes (r: - 0.337; p <0.01) and left eyes (r: -0.330; p <0.01) of females and age. There was no statistically significant relatiponship between right and left amplitude measurements and age in males (r:-0.183 r:-0.357; p>0.05).

Conclusion:

Amplitude decreased with increasing age in females, but no significant differences were found in latencies. There was not detected differences on latency and amplitude values in males with increasing age. Latencies in male were found to be longer when compared to female. It is thought that determination of community-based laboratory norms is important in evaluating the results and revealing normal values is also valuable.

Keywords: Normative VEP values, pattern VEP, P100 amplitude, P100 latency, age, gender