Research Article

Most Difficult Questions in Patients with Primary Enuresis Nocturna: Correct treatment? Right time?


  • Mehtap ÇELAKIL

Received Date: 20.01.2020 Accepted Date: 14.05.2020 Nam Kem Med J 2020;8(3):339-343


In this study, we aimed to evaluate the efficacy of combined desmopressin and behavior therapy in patients with monosymptomatic enuresis nocturna who had previously received short-term medical treatment retrospectively.

Materials and Methods:

The patients who were diagnosed as monosymptomatic enuresis nocturna by pediatricians were treated with desmopressin melt treatment for 1 month and 3 months and received complete or partial response. Desmopressin treatment and behavioral treatment were administered together for 6 months.


The mean age of the patients was 11 ± 2.1 (minimum 6, maximum 17 years). Of the 148 patients whose desmopressin + behavior therapy was completed for 6 months, 121 (%81,70) had complete dryness and 12 (%8,10) had partial response. Fifteen (%10.20) patients were evaluated as unresponsive. Recurrence was observed in 26 (%17,50) patients within 3 months after the end of treatment. 16 patients with relapse and unresponsive to treatment were <12 years of age.


Successful completion of treatment in enuresis nocturna and the addition of behavioral treatment to medical treatment is very important to reduce the risk of recurrence. The underlying neurological immaturity significantly affects the chances of success of the treatment.

Keywords: Enurezis nocturna, desmopressin, behavior therapy