Aim:

Lung cancer is the most common cancer in the world and is one of the leading causes of cancer-related deaths in both sexes. Despite improvements in treatment and duration of treatment, overall survival in these patients is still short. In this study, the demographic characteristics of patients with non-small cell metastatic lung cancer were examined and the effect of these factors on survival was evaluated.

Materials and Methods:

The study included 102 patients with metastatic non-small cell lung cancer who met the criteria for admission to study between 2010-2016 at Namık Kemal University Hospital Medical Oncology Clinic. Pre-treatment demographic characteristics of the patients were examined and a statistical analysis was performed to show the relationship between these characteristics and prognosis.

Results:

102 patients who met the Study Admission criteria were included in the study. Demographic characteristics of patients were recorded before treatment. Patients in the study group had a median overall survival time of 10 months and a median progression-free survival time of 6 months. When clinical parameters were examined, it was determined that patients had an ECOG Performance Score of 0-1, age ≥70, and that single metastasis was associated with longer overall survival. In multivariate cox regression analysis, only the number of metastases was found as an independent predictive value for survival.

Conclusion:

This study has shown that the number of metastases can help predict poor prognosis in patients with metastatic non-small cell lung cancer.

Keywords: small cell lung cancer, demographic characteristics, prognosis