Natriuretic peptide includes some neurohormones, such as atrial natriuretic peptides (ANP), B-type natriuretic peptides (BNP), C-type natriuretic peptides (CNP) and dendroapsis natriuretic peptides (DNP). There are released from by heart, brain, endothelium and other organs. The effects of these peptides are widespread, they plays a role regulations of natriuresis, diuresis, blood volume, blood pressure, fat metabolism, long bone growth and inhibition of cell proliferation. These biological actions are regulated through membrane-bound guanylyl cyclased receptors. In this review, the structure, function and physiological effects on various systems of natriuretic peptides are described.
Keywords: ANP, ANP receptors, ANP species