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Assessment of Methotrexate Efficacy in The Treatment of Ectopic Pregnancy
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Research Article
VOLUME: 7 ISSUE: 1
P: 25-30
April 2019

Assessment of Methotrexate Efficacy in The Treatment of Ectopic Pregnancy

Namik Kemal Med J 2019;7(1):25-30
Mehmet OBUT
M. Hanifi BADEMKIRAN
Sedat AKGÖL
Bekir KAHVECI
İhsan BAĞLI
S. Cemil OĞLAK
M. Şükrü BUDAK
1. Sağlik Bilimleri University, Gazi Yaşargil Education and Research Hospital, Clinic of Obstetrics and Gynecology, Diyarbakır, Turkey
No information available.
No information available
Received Date: 17.02.2019
Accepted Date: 23.03.2019
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ABSTRACT

Conclusions:

In our study, success rates in patients with EP treated with MTX were 80% after a single dose and as high as 90.7% when a second dose was added.

Results:

In total, 126 cases treated for EP were evaluated and 65 cases were included in the study. In cases administered a single dose of MTX, the success rate was 80%, the failure rate was 13.8%, and the emergency surgery rate was 6.2%. The overall success rate of the medical treatment was 90.7% for a second dose of MTX. An unsuccessful result was considered as less than a 15% reduction in the beta-human chorionic gonadotropin (β-hCG) level between 4 and 7 days after single dose MTX administration. In all cases, the rate of emergency surgery after treatment was 9.3%.

Materials and Methods:

Between September 2016 and August 2017, the treatment outcomes of EP cases treated with MTX at Gazi Yaşargil Training and Research Hospital of Health Sciences University were evaluated retrospectively.

Aim:

Our aim in this study was to assess efficacy of single-dose methotrexate (MTX) as medical treatment for ectopic pregnancy (EP) by evaluating the results of patients given this treatment.