Effect of Fluid Supplementation on Serum Bilirubin Level During Phototherapy of Exclusively Breastfed Term Infants with Hyperbilirubinemia
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Research Article
P: 188-195
December 2019

Effect of Fluid Supplementation on Serum Bilirubin Level During Phototherapy of Exclusively Breastfed Term Infants with Hyperbilirubinemia

Namik Kemal Med J 2019;7(3):188-195
1. Kocaeli Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları A.B.D, Kocaeli, TÜRKİYE
2. Tekirdağ Namık Kemal Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları A.B.D, Kocaeli, TÜRKİYE
3. Şanlıurfa Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Bölümü, Şanlıurfa, TÜRKİYE
4. Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Bölümü, İstanbul, TÜRKİYE
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Received Date: 28.06.2019
Accepted Date: 09.10.2019
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ABSTRACT

Conclusion:

Based on our results, intravenous fluid support has no effect on the rate of decrease in serum bilirubin and decrease in duration of phototherapy in healthy term newborns with no dehydration. However, using the oral route avoided the need for intravenous cannula and their attendant complications. Insensible fluid loss is increased during phototherapy, so protection of hydration status with oral feeding is important for newborns.

Results:

There were no significant differences (p>0.05) in the mean birth weight, mean gestastional age, modes of delivery, mean time of admission age, mean serum osmolality, and hematocrit and reticulocyte count between the two groups. Similarly, there was no significant difference (p>0.05) in the mean indirect serum bilirubin level at the time of admission to the neonatal intensive care unit and at 4, 8, 12, 24, and 48 hours after commencement of phototherapy between the two groups. There was no significant difference (p>0.05) in the mean duration of phototherapy or in the median duration of hospitalization between the two groups.

Materials and Methods:

A randomized controlled study was carried out in the neonatal intensive care unit of Zeynep Kamil Maternity and Children Training and Research Hospital (Istanbul, Turkey) over a 4-month period. Fifty healthy term infants with hyperbilirubinemia were randomized to receive either solely breastmilk (n=25) or both breastmilk and intravenous fluid (n=25) during phototherapy.

Aim:

This study compared the rates of decrease in serum bilirubin levels in severely jaundiced healthy term infants given oral or intravenous fluid supplementation during phototherapy.