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Evaluation of the Prevalence of Hepatitis B and C in Patients with Lymphoma
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Research Article
VOLUME: 8 ISSUE: 1
P: 48-51
April 2020

Evaluation of the Prevalence of Hepatitis B and C in Patients with Lymphoma

Namik Kemal Med J 2020;8(1):48-51
DOI: 10.37696/nkmj.632911
Mahmut BÜYÜKŞİMŞEK 1
Mustafa TOĞUN 2
Abdullah Evren YETİŞİR 1
Cem MİRİLİ 3
Ali OĞUL 4
Mert TOHUMCUOĞLU 1
Semra PAYDAŞ 1
1. Çukurova Üniversitesi Tıp Fakültesi, Medikal Onkoloji Bilim Dalı, Adana, TÜRKIYE
2. Çukurova Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilimdalı, Adana, TÜRKIYE
3. Erzurum Atatürk Üniversitesi Tıp Fakültesi, Medikal Onkoloji Bilim Dalı, Erzurum, TÜRKIYE
4. Adana Şehir Hastanesi, Medikal Onkoloji Bilim Dalı, Adana, TÜRKIYE
No information available.
No information available
Received Date: 14.10.2019
Accepted Date: 31.12.2019
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ABSTRACT

Aim:

Hepatitis enfection reactivation during chemotherapy is a major problem in lymphoma patients. We aimed to investigate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) in lymphoma patients treated in our center.

Materials and Methods:

The files of non-hodgkin lymphoma (NHL) and hodgkin lymphoma (HL) patients treated in our center between 2011-2018 were retrospectively reviewed. HBsAg, Anti-HBs, Anti-HBc and Anti-HCV parameters of the patients were evaluated.

Results:

In 21 (8.7%) of the 240 NHL patients, HBsAg antigen was positive. Anti-HCV positivity was detected in 9 patients (3.7%). In 79 (33%) patients, HBsAg (-), Anti-HBs (+) and Anti-HBc (+) were detected and evaluated as previous hepatitis B infection. In 10 (9.1%) of the 110 HL patients, HBsAg was positive and Anti-HCV positivity was detected in 3 patients (2.7%). In 29 (26.4%) patients, HBsAg (-), Anti-HBs (+) and Anti-HBc (+) were detected and evaluated as previous hepatitis B infection. When HBsAg and Anti-HCV positivity rates were compared between NHL and HL patient groups, no statistically significant difference was detected (p values were 0.9 and 0.63, respectively).

Conclusion:

According to the data of our country higher positivity of HBV and HCV was determined in lymphoma patients. Hepatitis B and C positivity in our region poses an important problem. Necessary information about vaccination and prevention methods should be provided.