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Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus
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Research Article
VOLUME: 3 ISSUE: 1
P: 6-14
April 2015

Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus

Namik Kemal Med J 2015;3(1):6-14
Birsen Aydemir 1
Ali Rıza Kızıler 2
F.Behice Cinemre 3
Hakan Cinemre 4
Abdullah Tüten 5
Mahmut Öncül 5
A. Serdar Açıkgöz 5
Gönül Gürol 6
1. Sakarya Üniversitesi Tıp Fakültesi, Biyofizik Anabilim Dalı, Sakarya
2. Namık Kemal Üniversitesi Tıp Fakültesi, Biyofizik Anabilim Dalı, Tekirdağ
3. Sakarya Üniversitesi Tıp Fakültesi, Biyokimya Anabilim Dalı, Sakarya
4. Sakarya Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Sakarya
5. İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul
6. Sakarya Üniversitesi Tıp Fakültesi, Fizyoloji Anabilim Dalı, Sakarya
No information available.
No information available
Received Date: 19.11.2014
Accepted Date: 06.01.2015
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ABSTRACT

Aim

The aim of the present study was to investigate levels of some biochemical and whole blood count parameters and plasma viscosity in women with gestational diabetes mellitus (GDM) compared to healthy pregnant and healthy, non-pregnant women, and to evaluate the relationships between plasma viscosity.

Material-Methods

The patients consisted of 27 pregnant with GDM. The control groups consisted of 25 healthy pregnant and 24 healthy non-pregnant women. Blood glucose, insulin, glycosylated hemoglobin (HbA1c), total cholesterol, triacylglycerol, LDL-cholesterol, HDL-cholesterol, total protein, albumin, HbA1c, Hct, Hb, PLT, MPV were measured by auto-analyzer. Also, plasma viscosity levels were measured by capillary viscometer.

Results

The levels of total protein, albumin, blood glucose, insulin, HOMAIR, HBA1c, total cholesterol, LDL-Cholesterol, HDL-Cholesterol and plazma viscosity in women with GDM group were found higher than those in healthy pregnant and non-pregnant women groups. In addition, the levels of triacylglycerol were significantly higher in GDM pregnants than those in the healthy pregnant women. There were significant positive correlations between plasma viscosity and total cholesterol levels of GDM patients. Additionally, there were significant positive correlations between plasma viscosity and LDL-cholesterol levels.

Conclusion

Plasma viscosity may contribute to useful information in early diagnosis and treatment, prevention of progression in GDM patients. It should be considered as an important parameter in clinical terms to ensure healthy fetal development.