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The Association Between Irritable Bowel Syndrome and Lactose Intolerance
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Research Article
VOLUME: 7 ISSUE: 3
P: 217-221
December 2019

The Association Between Irritable Bowel Syndrome and Lactose Intolerance

Namik Kemal Med J 2019;7(3):217-221
Mustafa Reşat DABAK 1
Tuğba ARSLAN KÜÇÜK 1
Sabah TÜZÜN 1
Hüseyin ÇETİN 1
Emel AHISHALI 2
Can DOLAPÇIOĞLU 3
1. Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Family Medicine, İstanbul, TURKEY
2. Koç University Hospital, Department of Gastroenterology, İstanbul, TURKEY
3. Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Gastroenterology, İstanbul, TURKEY
No information available.
No information available
Received Date: 24.05.2019
Accepted Date: 07.11.2019
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ABSTRACT

Conclusion:

A significantly increased frequency of LI was found among IBS patients than in controls. In addition, symptoms associated with lactose intake occurred at a higher frequency in IBS patient, although the difference was insignificant.

Results:

Of the total 200 participants, 100 (50%) were in the IBS group and 100 (50.0%) were in the control group. Of the total 70 patients (35.0%) with LI, 47 (47.0%) were in the IBS group and 23 (23.0%) were in the control group (p=0.001). Symptoms related to IBS were more common in participants with LI in both groups (p=0.001, p=0.001 respectively).

Materials and Methods:

The patient population consisted of individuals between 18 and 80 years of age who attended between June-December 2013. Patients diagnosed with IBS based on Roma III criteria comprised the IBS group, and subtypes of IBS. Control group was healthy volunteers over 18 years of age with no IBS-like symptoms. All participants ingested 25 g of lactose dissolved in 250 ml of water within 5 minutes after 8 hours of fasting, in order to evaluate the LI via hydrogen breath test (0, 15, 30, 60, 90, and 120 minutes).

Aim:

Irritable bowel syndrome (IBS) and lactose intolerance (LI) may co-exist and readily cause diagnostic confusion due to similar symptomatology. This study aims to examine the frequency of LI in healthy controls and in participants diagnosed with IBS based on Roma III criteria, as an effort to investigate the association between IBS and LI.