ÖZ
Amaç
Bu çalışmada, obezitenin kronik rinosinüzitli (KRS) hastalardaki semptom profili ve radyolojik hastalık yükü üzerindeki etkisini değerlendirmek amaçlandı.
Gereç ve Yöntem
Toplam 123 KRS hasta, geriye dönük olarak analiz edildi. Olguların boy, kilo, 22-öğelik Sinonazal Sonuç testi (SNOT-22) testi ve Lund-Mackay skorları not edildi. Hastalar vücut kitle indeksi (VKİ) değerlerine göre obez (≥30 kg/m2) ve normal (<30 kg/m2) olarak gruplandırıldı. Semptom profilleri SNOT-22 ile, radyolojik hastalık yükü ise Lund-Mackay skorlaması ile değerlendirildi. VKİ ile SNOT-22’nin her bir sorusu ve toplam SNOT-22 skoru Spearman korelasyon, Lund-Mackay skoru ise Pearson korelasyon analizi ile incelendi.
Bulgular
VKİ artışı bazı SNOT-22 maddeleri ile anlamlı pozitif korelasyon gösterdi; bu ilişkiler kadınlarda burun tıkanıklığı ve uykuya ilişkin semptomlarda, erkeklerde ise geniz akıntısında daha belirgindi. Ancak obez ve normal gruplar karşılaştırıldığında toplam SNOT-22 ve Lund-Mackay skorlarında anlamlı fark saptanmadı.
Sonuç
Obezite, toplam semptom yükünü belirgin olarak artırmamakla birlikte belirli semptom paternleri ile ilişkili olabilir. Kadınlarda obezitenin obstrüktif semptomları, erkeklerde ise sekretuar semptomları ön plana çıkarması, bu hasta grubunda kişiselleştirilmiş tedavi yaklaşımlarının gerekliliğini ortaya koymaktadır. Obezitenin KRS semptomları, fenotipleri ve radyolojik bulguları üzerindeki etkisini daha net ortaya koymak için geniş örneklemli çalışmalara ihtiyaç vardır.
Anahtar Kelimeler:
Kronik rinosinüzit, obezite, vücut kitle indeksi, SNOT-22
Kaynaklar
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